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Extensive Mendelian randomization study identifies potential causal risk factors for severe COVID-19

9 Dec 2021

Abstract excerpt

Background: Identifying causal risk factors for severe coronavirus disease 2019 (COVID-19) is critical for its prevention and treatment. Many associated pre-existing conditions and biomarkers have been reported, but these observational associations suffer from confounding and reverse causation. Methods: Here, we perform a large-scale two-sample Mendelian randomization (MR) analysis to evaluate the causal roles of...

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PMID: 35602208
DOI: 10.1038/s43856-021-00061-9

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