Article
Association of functional genetic variants in TFF1 and nephrolithiasis risk in a Chinese population.
BMC urology - 20 Aug 2022
Wang Qiangdong, Jiang Yan, Du Mulong, Yang Lei, Yuan Qinbo
Abstract excerpt
Trefoil Factor 1 (TFF1) is considered to be able to inhibit the formation of kidney stone. However, genetic variants in TFF1 and corresponding function in kidney stone development are still not well studied. In this study, the discovery set including 230 cases and 250 controls was used to analyze the association between seven tagSNPs of TFF1 gene and the nephrolithiasis risk. Further evaluation was confirmed by...
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