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Article

FKBP1A rs6041749 polymorphism is associated with allograft function in renal transplant patients.

European journal of clinical pharmacology - 1 Jan 2019

Wu Zhuo, Xu Qinxia, Qiu Xiaoyan, Xu Luyang, Jiao Zheng, Zhang Ming, Zhong Mingkang

Abstract excerpt

AIM: To investigate the potential impact of single-nucleotide polymorphisms (SNPs) in the FK506-binding protein (FKBP)-calcineurin (CaN)-nuclear factor of activated T cells (NFAT) signaling pathway on the efficacy and safety of tacrolimus (TAC) in Chinese renal transplant patients. METHODS: Seventy-seven tag SNPs were detected in 146 patients who were on TAC-based maintenance immunosuppression and who followed up...

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PMID: 30215102
DOI: 10.1007/s00228-018-2546-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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