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Article

Total mutational load and clinical features as predictors of the metastatic status in lung adenocarcinoma and squamous cell carcinoma patients.

Journal of translational medicine - 18 Aug 2022

Oróstica Karen Y, Saez-Hidalgo Juan, de Santiago Pamela R, Rivas Solange, Contreras Sebastian, Navarro Gonzalo, Asenjo Juan A, Olivera-Nappa Álvaro, Armisén Ricardo

Abstract excerpt

BACKGROUND: Recently, extensive cancer genomic studies have revealed mutational and clinical data of large cohorts of cancer patients. For example, the Pan-Lung Cancer 2016 dataset (part of The Cancer Genome Atlas project), summarises the mutational and clinical profiles of different subtypes of Lung Cancer (LC). Mutational and clinical signatures have been used independently for tumour typification and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35982500
DOI: 10.1186/s12967-022-03572-8
PMCID: PMC9389677

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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