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Prognostic impact of tumour mutational burden in resected stage I and II lung adenocarcinomas from a European Thoracic Oncology Platform Lungscape cohort.

Lung cancer (Amsterdam, Netherlands) - 1 Dec 2022

Bubendorf Lukas, Zoche Martin, Dafni Urania, Rüschoff Jan Hendrik, Prince Spasenija Savic, Marti Nesa, Stavrou Androniki, Kammler Roswitha, Finn Stephen P, Moch Holger, Peters Solange, Stahel Rolf A

Abstract excerpt

BACKGROUND: The primary objective of this study is to evaluate tumor mutational burden (TMB), its associations with selected clinicopathological and molecular characteristics as well as its clinical significance, in a retrospective cohort of surgically resected stage I-II lung adenocarcinomas, subset of the ETOP Lungscape cohort. METHODS: TMB was evaluated on tumor DNA extracted from resected primary lung...

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PMID: 36283211
DOI: 10.1016/j.lungcan.2022.09.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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