Article
Extensive prediction of drug response in mutation-subtype-specific LUAD with machine learning approach.
Oncology research - 1 Jan 2023
Jia Kegang, Wang Yawei, Cao Q I, Wang Youyu
Abstract excerpt
Background: Lung cancer is the most prevalent cancer diagnosis and the leading cause of cancer death worldwide. Therapeutic failure in lung cancer (LUAD) is heavily influenced by drug resistance. This challenge stems from the diverse cell populations within the tumor, each having unique genetic, epigenetic, and phenotypic profiles. Such variations lead to varied therapeutic responses, thereby contributing to...
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