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Article

Mutation load estimation model as a predictor of the response to cancer immunotherapy

25 Apr 2018

Abstract excerpt

Abstract The determination of the mutation load, a total number of nonsynonymous point mutations, by whole-exome sequencing was shown to be useful in predicting the treatment responses to cancer immunotherapy. However, this technique is expensive and time-consuming, which hampers its application in clinical practice. Therefore, the objective of this study was to construct a mutation load estimation model for lung...

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PMID: 29736260
DOI: 10.1038/s41525-018-0051-x

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