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Article

Metabolic, genetic, and pharmacokinetic parameters for the prediction of olanzapine efficacy.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences - 1 Oct 2022

Cong Ling, Wan Zirui, Li Pengfei, Liu Dan, He Jiuming, An Zhuoling, Liu Lihong

Abstract excerpt

Clinical use of the a olanzapine has significantly different individual-to-individual outcomes. Accordingly, this study aimed to develop a means of predicting response to olanzapine using a combined approach based on pharmacokinetics, pharmacometabonomics, and genetic polymorphism. The olanzapine pharmacokinetics of 19 healthy volunteers treated with orally disintegrating tablets were determined using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35981664
DOI: 10.1016/j.ejps.2022.106277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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