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Article

The pharmacogenetics of treatment with olanzapine

1 Sept 2021

Abstract excerpt

Genetic polymorphism in olanzapine-metabolizing enzymes, transporters and drug targets is associated with alterations in safety and efficacy. The aim of this systematic review is to describe all clinically relevant pharmacogenetic information on olanzapine and to propose clinically actionable variants. Two hundred and eighty-four studies were screened; 76 complied with the inclusion criteria and presented...

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PMID: 34528455
DOI: 10.2217/pgs-2021-0051

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