Article

Pharmacogenetic and Pharmacogenomic Research in Psychiatry: Current Advances and Clinical Applications.

2003-09-01

Abstract excerpt

After more than 50 years of investigations, pharmacogenetic efforts have crystallized in several findings relating genetically determined pharmacokinetic and pharmacodynamic factors to treatment response. Metabolic enzymes and neurotransmitter proteins contain genetic polymorphisms that alter their interaction with psychotropic drugs and contribute to response variability. This knowledge can be used to predict cli...

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Literature Corpus work: 7879401a-55e2-52f1-a7e2-1b3813553ed4
DOI: 10.2174/1570160033476287

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