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Article

Clonal haematopoiesis of indeterminate potential-related mutations and outcome in dilated and ischaemic cardiomyopathy.

ESC heart failure - 1 Dec 2022

Wu Jasmine M F, Bekfani Tarek, Hinze Anna, Westphal Julian Georg, Steinacker Berit, Zeller Max, Hartmann Charlotte, Möbius-Winkler Sven, Hochhaus Andreas, Schulze P Christian, Ernst Thomas

Abstract excerpt

AIMS: Clonal haematopoiesis of indeterminate potential (CHIP)-associated mutation is a risk factor for the development of ischaemic cardiomyopathy (ICM), but its association with non-ischaemic dilated cardiomyopathy (DCM) remains unclear. We aimed to determine the prevalence of CHIP in patients with DCM and define its risk for disease progression. METHODS AND RESULTS: Next-generation sequencing targeting 54...

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PMID: 35979940
DOI: 10.1002/ehf2.14115
PMCID: PMC9773636

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