Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromosomal instability in adult-type diffuse gliomas.

Acta neuropathologica communications - 17 Aug 2022

Richardson Timothy E, Walker Jamie M, Abdullah Kalil G, McBrayer Samuel K, Viapiano Mariano S, Mussa Zarmeen M, Tsankova Nadejda M, Snuderl Matija, Hatanpaa Kimmo J

Abstract excerpt

Chromosomal instability (CIN) is a fundamental property of cancer and a key underlying mechanism of tumorigenesis and malignant progression, and has been documented in a wide variety of cancers, including colorectal carcinoma with mutations in genes such as APC. Recent reports have demonstrated that CIN, driven in part by mutations in genes maintaining overall genomic stability, is found in subsets of adult-type...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal Instability
Share to APC gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioma

Share to Glioma Diagnosis and Treatment

Share to Microtubule and mitosis dynamics

Share to Mutation

Share to Pancreatic and Hepatic Oncology Research

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 35978439
DOI: 10.1186/s40478-022-01420-w
PMCID: PMC9386991

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromosomal instability in adult-type diffuse gliomas.PMID 35978439Read ↗

Chromosomal instability: a key driver in glioma pathogenesis and progressionSemantic proximity Read ↗

Genomic landscape of diffuse glioma revealed by whole genome sequencingSemantic proximity Read ↗

Molecular Signatures of Chromosomal Instability Correlate With Copy Number Variation Patterns and Patient Outcome in IDH-Mutant and IDH-Wildtype Astrocytomas.Semantic proximity Read ↗

Genetic alterations in adult diffuse glioma: occurrence, significance, and prognostic implicationsSemantic proximity Read ↗

Genomic landscape of diffuse glioma revealed by whole genome sequencingSemantic proximity Read ↗

Longitudinal molecular trajectories of diffuse glioma in adults.Semantic proximity Read ↗

Elevated signature of a gene module coexpressed with CDC20 marks genomic instability in gliomaSemantic proximity Read ↗

Global DNA methylation profiling reveals chromosomal instability in IDH-mutant astrocytomas.Semantic proximity Read ↗

The Role of Chromosomal Instability in Cancer and Therapeutic ResponsesSemantic proximity Read ↗

Signatures of chromosomal instability in human cancersSemantic proximity Read ↗

Genetic and molecular epidemiology of adult diffuse gliomaSemantic proximity Read ↗

Genetic alterations associated with adult diffuse astrocytic tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.