Article
Post-translational control of beige fat biogenesis by PRDM16 stabilization
17 Aug 2022
Abstract excerpt
Abstract Compelling evidence shows that brown and beige adipose tissue are protective against metabolic diseases 1,2 . PR domain-containing 16 (PRDM16) is a dominant activator of the biogenesis of beige adipocytes by forming a complex with transcriptional and epigenetic factors and is therefore an attractive target for improving metabolic health 3–8 . However, a lack of knowledge surrounding the regulation of...
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