Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A case of progressive multifocal leukoencephalopathy with hypogammaglobulinemia and a TCF3 mutation.

Journal of neurovirology - 1 Dec 2022

Li Qiong, Tang Chunhua, Zhu Jie, Zhang Lili

Abstract excerpt

Progressive multifocal leukoencephalopathy (PML) is a rare and potentially fatal demyelinating disease of the central nervous system (CNS) caused by JC virus; it was previously seen predominantly in immunocompromised patients and those under intense immune suppression. Here, we report the case of a patient with PML with hypogammaglobulinemia and a heterozygous mutation in the TCF3 gene. As the TCF3 gene has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Agammaglobulinemia
Share to Basic Helix-Loop-Helix Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Common Variable Immunodeficiency

Share to JC Virus

Share to Leukoencephalopathy, Progressive Multifocal

Share to Mutation

Source

Identifiers

PMID: 35976539
DOI: 10.1007/s13365-022-01092-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A case of progressive multifocal leukoencephalopathy with hypogammaglobulinemia and a TCF3 mutation.PMID 35976539Read ↗

Progressive multifocal leukoencephalopathy in a patient with novel mutation in the RAC2 gene: a case report.Semantic proximity Read ↗

Progressive Multifocal LeukoencephalopathySemantic proximity Read ↗

Progressive Multifocal Leukoencephalopathy in Primary Immune Deficiencies: Stat1 Gain of Function and Review of the Literature.Semantic proximity Read ↗

Pathogenesis of Progressive Multifocal Leukoencephalopathy—RevisitedSemantic proximity Read ↗

Homozygous transcription factor 3 gene (TCF3) mutation is associated with severe hypogammaglobulinemia and B-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

Progressive Multifocal Leukoencephalopathy: Molecular Biology, Pathogenesis and Clinical ImpactSemantic proximity Read ↗

[New trends in progressive multifocal leukoencephalopathy].Semantic proximity Read ↗

Inadequate Immune Humoral Response against JC Virus in Progressive Multifocal Leukoencephalopathy Non-Survivors.Semantic proximity Read ↗

Long-Term Survival after Progressive Multifocal Leukoencephalopathy in a Patient with Primary Immune Deficiency and NFKB1 Mutation.Semantic proximity Read ↗

Detection of JC virus in two African cases of progressive multifocal leukoencephalopathy including identification of JCV type 3 in a Gambian AIDS patient.Semantic proximity Read ↗

Progressive multifocal leukoencephalopathy and JC virus genotypes in West African patients with acquired immunodeficiency syndrome: a pathologic and DNA sequence analysis of 4 cases.Semantic proximity Read ↗

[Detection of novel rearrangement of the JC virus gene in a case of progressive multifocal leukoencephalopathy with adult T-cell leukemia].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.