Article
Causal analysis of serum polyunsaturated fatty acids with juvenile idiopathic arthritis and ocular comorbidity.
European journal of clinical nutrition - 1 Jan 2023
Shu Qinxin, Zhao Chenyang, Yu Jing, Liu Yusen, Hu Shuqiong, Meng Jiayu, Zhang Jun
Abstract excerpt
BACKGROUND & OBJECTIVE: To investigate the causal effects of plasma Polyunsaturated fatty acids (PUFAs) on the risk of juvenile idiopathic arthritis (JIA) and ocular comorbidity through Mendelian randomization (MR) analysis. METHODS: Genetic variants (formerly single nucleotide polymorphisms, SNPs) that are strongly associated with PUFAs levels (P < 5×10-8) were selected as instrumental variables. Summary-level...
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