Adaptation to novel spatially-structured environments is driven by the capsule and alters virulence-associated traits.

doi:10.1038/s41467-022-32504-9

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Article

Adaptation to novel spatially-structured environments is driven by the capsule and alters virulence-associated traits.

Nature communications - 13 Aug 2022

Nucci Amandine, Rocha Eduardo P C, Rendueles Olaya

Abstract excerpt

The extracellular capsule is a major virulence factor, but its ubiquity in free-living bacteria with large environmental breadths suggests that it shapes adaptation to novel niches. Yet, how it does so, remains unexplored. Here, we evolve three Klebsiella strains and their capsule mutants in para...

Topics

Acclimatization
Genotype
Mutation
Phenotype
Virulence

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