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Benefits and costs of a hypercapsule and the mechanism of its loss in a clinical isolate of Acinetobacter baumannii.

mBio - 11 Feb 2026

Saren Chaogetu, Oinuma Ken-Ichi, Tsubouchi Taishi, Sakiyama Arata, Suzuki Masato, Niki Mamiko, Kaneko Yukihiro

Abstract excerpt

Acinetobacter baumannii is an opportunistic pathogen in which capsule production is closely linked to immune evasion and environmental persistence. Recent studies have described two seemingly contradictory phenomena-increasing prevalence of capsule-overproducing clinical isolates and frequent isolation of capsule-deficient variants. The biological significance of these phenomena remains unclear. In this study, we...

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Acinetobacter baumannii
Acinetobacter Infections
Bacterial Capsules
Genome, Bacterial
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Whole Genome Sequencing

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PMID: 41459967
DOI: 10.1128/mbio.02366-25
PMCID: PMC12892936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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