Article
Phenotypic heterogeneity of capsule production across opportunistic pathogens.
mBio - 8 Oct 2025
Nucci Amandine, Le Bris Julie, Diaz-Diaz Sara, Torres-Elizalde Lilibeth, Rocha Eduardo P C, Rendueles Olaya
Abstract excerpt
Phenotypic heterogeneity allows bacteria to adapt fast to changing environments. Extracellular capsules are well-known virulence factors, but also increase the cell adaptability and prevalence under hostile conditions. To limit their cost, some species regulate capsule production by genetic phase variation. Here, we demonstrated that phenotypic heterogeneity is a major mechanism controlling capsule production in...
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