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The wzc mutation mediates virulence changes in K1-type Klebsiella pneumoniae within the same patient

15 May 2025

Abstract excerpt

Hypervirulent Klebsiella pneumoniae (hvKp) is a major pathogen causing community-acquired infections, particularly severe diseases such as liver abscesses. Although extensive research has been conducted on the virulence mechanisms of hvKp and the genetic properties of resistance plasmids, studies on the adaptive evolution of clinical strains within the host are still limited. This study aimed to investigate the...

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PMID: 40444005
DOI: 10.3389/fmicb.2025.1577629

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