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Article

Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01

1 Sept 2021

Abstract excerpt

Background Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, there has been increasing urgency to identify pathophysiological characteristics leading to severe clinical course in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Human leukocyte antigen alleles (HLA) have been suggested as potential genetic host factors that affect individual immune...

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PMID: 34490415
DOI: 10.1016/j.eclinm.2021.101099

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