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Conformational stability of SARS-CoV-2 glycoprotein spike variants

30 Nov 2022

Abstract excerpt

The severe acute respiratory syndrome spread worldwide, causing a pandemic. SARS-CoV-2 mutations have arisen in the spike, a glycoprotein at the viral envelope and an antigenic candidate for vaccines against COVID-19. Here, we present comparative data of the glycosylated full-length ancestral and D614G spike together with three other transmissible strains classified by the World Health Organization as variants of...

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PMID: 36465857
DOI: 10.1016/j.isci.2022.105696

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