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Detection of Plasmid-Mediated Resistance to Metronidazole in Clostridioides difficile from River Water

11 Aug 2022

Abstract excerpt

The combination of direct plating and culture after enrichment was used in order to gain a spectrum of C. difficile ribotypes present in the water samples. Toxigenic C. difficile ribotypes detected in surface water and in wastewater treatment plants overlapped with those derived from patients with CDI and/or animals. Importantly, a recently discovered plasmid-mediated resistance to metronidazole, a drug used for...

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PMID: 35950844
DOI: 10.1128/spectrum.00806-22

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