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Article

Immune phenotypes and checkpoint molecule expression of clonally expanded lymph node-infiltrating T cells in classical Hodgkin lymphoma.

Cancer immunology, immunotherapy : CII - 1 Feb 2023

Ballhausen Alexej, Ben Hamza Amin, Welters Carlotta, Dietze Kerstin, Bullinger Lars, Rahn Hans-Peter, Hartmann Sylvia, Hansmann Martin-Leo, Hansmann Leo

Abstract excerpt

Lymph node-infiltrating T cells have been of particular interest in classical Hodgkin lymphoma (cHL). High rates of complete therapeutic responses to antibody-mediated immune checkpoint blockade, even in relapsed/refractory patients, suggest the existence of a T cell-dominated, antigen-experienced, functionally inhibited and lymphoma-directed immune microenvironment. We asked whether clonally expanded T cells...

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Share to CD8-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune Checkpoint Inhibitors

Share to Lymph Nodes

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Source

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Identifiers

PMID: 35947165
DOI: 10.1007/s00262-022-03264-8
PMCID: PMC9870823

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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