Performance of a multigene genomic classifier and clinical parameters in predicting malignancy in a Southeast Asian cohort of patients with cytologically indeterminate thyroid nodules.

doi:10.1002/cncy.22796

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Performance of a multigene genomic classifier and clinical parameters in predicting malignancy in a Southeast Asian cohort of patients with cytologically indeterminate thyroid nodules.

Cancer cytopathology - 1 May 2024

Yang Samantha Peiling, Nga Min En, Bundele Manish Mahadeorao, Chiosea Simion I, Tan Sze Hwa, Lum Jeffrey H Y, Parameswaran Rajeev, Lim Ming Yann, Li Hao, Cheah Wei Keat, Sek Kathleen Su-Yen, Tan Andre Teck Huat, Loh Thomas Kwok Seng, Ngiam Kee Yuan, Tan Wee Boon, Huang Xinyong, Ho Thomas Wai Thong, Lim Keng Hua, Lim Chwee Ming, Singaporewalla Reyaz M, Rao Anil Dinkar, Rao Nandini C L, Chua Dennis Yu Kim, Chin David Chao-Wu, Wald Abigail I, LiVolsi Virginia A, Nikiforov Yuri E, Tai E Shyong

Abstract excerpt

BACKGROUND: Most thyroid nodules are benign. It is important to determine the likelihood of malignancy in such nodules to avoid unnecessary surgery. The primary objective of this study was to characterize the genetic landscape and the performance of a multigene genomic classifier in fine-needle aspiration (FNA) biopsies of cytologically indeterminate thyroid nodules in a Southeast Asian cohort. The secondary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asia, Southeastern

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Biopsy, Fine-Needle

Share to Genomics

Share to Prognosis

Share to Southeast Asian People

Share to Thyroid Neoplasms

Share to Thyroid Nodule

Source

Open in PubMed

Identifiers

PMID: 38319805
DOI: 10.1002/cncy.22796

Genes

BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Performance of a multigene genomic classifier and clinical parameters in predicting malignancy in a Southeast Asian cohort of patients with cytologically indeterminate thyroid nodules.PMID 38319805Read ↗

High-risk and intermediate-high-risk results from the ThyroSeq v2 and v3 thyroid genomic classifier are associated with neoplasia: Independent performance assessment at an academic institution.Semantic proximity Read ↗

Risk stratification of indeterminate thyroid nodules by novel multigene testing: a study of Asians with a high risk of malignancy.Semantic proximity Read ↗

Clinical value of multi-gene testing in distinguishing benign and malignant thyroid nodules.Semantic proximity Read ↗

Correlation of ThyroSeq Results with Surgical Histopathology in Cytologically Indeterminate Thyroid Nodules.Semantic proximity Read ↗

Molecular Profiling for Bethesda III to VI Nodules: Results of a Multicenter International Retrospective Study.Semantic proximity Read ↗

Molecular Profiling of 50 734 Bethesda III-VI Thyroid Nodules by ThyroSeq v3: Implications for Personalized Management.Semantic proximity Read ↗

Utilities of RAS Mutations in Preoperative Fine Needle Biopsies for Decision Making for Thyroid Nodule Management: Results from a Single-Center Prospective Cohort.Semantic proximity Read ↗

Inter-institutional variation in predictive value of the ThyroSeq v2 genomic classifier for cytologically indeterminate thyroid nodulesSemantic proximity Read ↗

Clinical value of multi-gene testing in distinguishing benign and malignant thyroid nodulesSemantic proximity Read ↗

Diagnostic Utility of a Cost-Effective Four-Gene Next Generation Sequencing Panel for Predicting Papillary Thyroid Carcinoma in Indeterminate Thyroid Cytology: A Multicenter Study in China.Semantic proximity Read ↗

ThyroSeq overview on indeterminate thyroid nodules: An institutional experience.Semantic proximity Read ↗

Clinical utility of a microRNA classifier in cytologically indeterminate thyroid nodules with RAS mutations: A multi-institutional study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.