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Article

Prospective Validation of ThyroSPEC Molecular Testing of Indeterminate Thyroid Nodule Cytology Following Diagnostic Pathway Optimization.

Thyroid : official journal of the American Thyroid Association - 1 Dec 2023

Stewardson Paul, Eszlinger Markus, Wu Jiahui, Khalil Moosa, Box Adrian, Perizzolo Marco, Punjwani Zoya, Ziehr Bjoern, Sanyal Ratna, Demetrick Douglas J, Paschke Ralf

Abstract excerpt

Background: Molecular testing for cytologically indeterminate thyroid nodules (ITNs) is often reported with incomplete data on clinical assessment and ultrasound malignancy risk (USMR) stratification. This study aimed to clinically validate the diagnostic accuracy of a novel molecular test, assess the incremental preoperative malignancy risk of other clinical factors, and measure the impacts of introducing...

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Identifiers

PMID: 37742115
DOI: 10.1089/thy.2023.0255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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