Article
Human Fetal Cartilage-Derived Progenitor Cells Exhibit Anti-Inflammatory Effect on IL-1β-Mediated Osteoarthritis Phenotypes In Vitro.
Tissue engineering and regenerative medicine - 1 Dec 2022
Kim Jiyoung, Tran An Nguyen-Thuy, Lee Ji Young, Park Sang-Hyug, Park So Ra, Min Byoung-Hyun, Choi Byung Hyune
Abstract excerpt
BACKGROUND: In this study, we have investigated whether human fetal cartilage progenitor cells (hFCPCs) have anti-inflammatory activity and can alleviate osteoarthritis (OA) phenotypes in vitro. METHODS: hFCPCs were stimulated with various cytokines and their combinations and expression of paracrine factors was examined to find an optimal priming factor. Human chondrocytes or SW982 synoviocytes were treated with...
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