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Generation of human induced pluripotent stem cells from osteoarthritis patient-derived synovial cells

27 Sept 2011

Abstract excerpt

OBJECTIVE: This study was undertaken to generate and characterize human induced pluripotent stem cells (PSCs) from patients with osteoarthritis (OA) and to examine whether these cells can be developed into disease-relevant cell types for use in disease modeling and drug discovery. METHODS: Human synovial cells isolated from two 71-year-old women with advanced OA were characterized and reprogrammed into induced...

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PMID: 21953087
DOI: 10.1002/art.30488

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