Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors

27 Jan 2023

Abstract excerpt

Developmentally, the articular joints are derived from lateral plate (LP) mesoderm. However, no study has produced both LP derived prechondrocytes and preosteoblasts from human pluripotent stem cells (hPSC) through a common progenitor in a chemically defined manner. Differentiation of hPSCs through the authentic route, via an LP-osteochondral progenitor (OCP), may aid understanding of human cartilage development...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to MicroRNA in disease regulation
Share to Osteoarthritis Treatment and Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36706111
DOI: 10.1371/journal.pone.0280024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitorsPMID 36706111Read ↗

Directed differentiation of hPSCs through lateral plate mesoderm for generation of articular cartilage progenitorsSemantic proximity Read ↗

Comparison of Four Protocols to Generate Chondrocyte-Like Cells from Human Induced Pluripotent Stem Cells (hiPSCs)Semantic proximity Read ↗

Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cellsSemantic proximity Read ↗

Lateral Mesoderm-Derived Mesenchymal Stem Cells With Robust Osteochondrogenic Potential and Hematopoiesis-Supporting AbilitySemantic proximity Read ↗

Directed Differentiation of Notochord-like and Nucleus Pulposus-like Cells Using Human Pluripotent Stem CellsSemantic proximity Read ↗

Development of pluripotent stem cell‐based human tenocytesSemantic proximity Read ↗

Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cellsSemantic proximity Read ↗

Generating Cartilage Repair from Pluripotent Stem CellsSemantic proximity Read ↗

Derivation of Isogenic Mesodermal and Ectomesodermal Chondrocytes from Human Induced Pluripotent Stem Cells for Articular Cartilage RegenerationSemantic proximity Read ↗

Human Developmental Chondrogenesis as a Basis for Engineering Chondrocytes from Pluripotent Stem CellsSemantic proximity Read ↗

Modeling human limb skeletal development using human pluripotent stem cell-derived skeletal assembloidsSemantic proximity Read ↗

Engineering Musculoskeletal Tissues with Human Embryonic Germ Cell DerivativesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.