Article
Mu heavy chain disease with MYD88 L265P mutation: an unusual manifestation of lymphoplasmacytic lymphoma.
Diagnostic pathology - 5 Aug 2022
Baloda Vandana, Wheeler Sarah E, Murray David L, Kohlhagen Mindy C, Vos Jeffrey A, Yatsenko Svetlana A, Agha Mounzer E, Djokic Miroslav, Swerdlow Steven H, Bailey Nathanael G
Abstract excerpt
BACKGROUND: Mu heavy chain disease is a rare lymphoid neoplasm characterized by vacuolated bone marrow plasma cells and secretion of defective mu immunoglobulin heavy chains. The biological basis of mu heavy chain disease is poorly understood. CASE PRESENTATION: We report a case of mu heavy chain disease with MYD88 L265P mutation and deletion of 6q, genetic aberrations that are both strongly associated with...
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