Article
Detection of MYD88 L265P mutations in formalin-fixed and decalcified BM biopsies from patients with lymphoplasmacytic lymphoma.
Experimental and molecular pathology - 1 Aug 2014
Capaldi Ianina Belén, May Annette M, Schmitt-Graeff Annette, Follo Marie, Aumann Konrad, Kayser Gian, Perazzo Juan Carlos, Werner Martin, Fisch Paul
Abstract excerpt
The diagnosis of bone marrow (BM) infiltration by Waldenström macroglobulinemia (WM)/lymphoplasmacytic lymphoma (LPL) poses a diagnostic challenge in hematopathology. No definitive morphology or immunophenotype is able to distinguish between infiltration of paraffin-embedded BM sections by WM/LPL and other indolent lymphomas, in particular those of the splenic marginal zone (SMZL) which may also show plasmacytic...
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