Article
Insights into the microevolution of SARS-ACE2 interactions: in silico analysis of glycosylation and SNP pattern.
Journal of biomolecular structure & dynamics - 1 Jan 2000
Madasu Pavan K, Maity Arpita, Ghosh Surya K, Chandran Thyageshwar
Abstract excerpt
The prefatory protein-glycan interaction and stabilizing protein-protein interaction of severe acute respiratory syndrome viruses with angiotensin-converting enzyme 2 play a significant role in complex formation thereby promoting endocytosis. The microevolution of SARS-CoV-2 over a period of time has a significant role in increasing the affinity of receptor-binding domain against angiotensin converting-enzyme 2....
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