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Article

Clinical significance and interrelations of PD-L1 expression, Ki-67 index, and molecular alterations in sporadic medullary thyroid carcinoma from a Chinese population.

Virchows Archiv : an international journal of pathology - 1 Dec 2022

Bai Yanhua, Guo Ting, Niu Dongfeng, Zhu Yanli, Ren Wenhao, Yao Qian, Huang Xiaozheng, Feng Qin, Wang Tianxiao, Ma Xiuli, Ji Xinqiang

Abstract excerpt

Immunotherapy shows prospects in treating advanced medullary thyroid carcinoma although controversial reports are present. Recently, histological grading has been applied to medullary thyroid carcinoma by the Ki-67 index, mitotic figures, and tumor necrosis. However, the interrelation of PD-L1 expression, the Ki-67 index, and major genetic alterations of sporadic medullary thyroid carcinoma has not been fully...

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PMID: 35920918
DOI: 10.1007/s00428-022-03390-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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