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Article

PD-L1 and PD-1 expression are correlated with distinctive clinicopathological features in papillary thyroid carcinoma.

Diagnostic pathology - 3 Oct 2017

Bai Yanhua, Niu Dongfeng, Huang Xiaozheng, Jia Ling, Kang Qiang, Dou Fangyuan, Ji Xinqiang, Xue Weicheng, Liu Yiqiang, Li Zhongwu, Feng Qin, Lin Dongmei, Kakudo Kennichi

Abstract excerpt

BACKGROUND: Immune checkpoint blockade targeting PD-1/PD-L1 has shown efficacy in several types of cancers. However, the correlation between PD-L1/PD-1 expression and the specific clinicopathological features in papillary thyroid carcinoma (PTC) has not been investigated. METHODS: We examined the immunohistochemical expression of PD-L1, PD-1, and BRAF V600E on whole-tissue sections from 126 cases of primary PTC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Papillary

Share to Lymphocytes, Tumor-Infiltrating

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Source

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Identifiers

PMID: 28974264
DOI: 10.1186/s13000-017-0662-z
PMCID: PMC5627454

Genes

BRAF

Variants

Provenance

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