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Rewriting cellular fate: epigenetic interventions in obesity and cellular programming

10 Oct 2024

Abstract excerpt

External constraints, such as development, disease, and environment, can induce changes in epigenomic patterns that may profoundly impact the health trajectory of fetuses and neonates into adulthood, influencing conditions like obesity. Epigenetic modifications encompass processes including DNA methylation, covalent histone modifications, and RNA-mediated regulation. Beyond forward cellular differentiation (cell...

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PMID: 39390356
DOI: 10.1186/s10020-024-00944-2

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