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Article

Raman spectroscopy reveals phenotype switches in breast cancer metastasis.

Theranostics - 1 Jan 2022

Paidi Santosh Kumar, Troncoso Joel Rodriguez, Harper Mason G, Liu Zhenhui, Nguyen Khue G, Ravindranathan Sruthi, Rebello Lisa, Lee David E, Ivers Jesse D, Zaharoff David A, Rajaram Narasimhan, Barman Ishan

Abstract excerpt

The accurate analytical characterization of metastatic phenotype at primary tumor diagnosis and its evolution with time are critical for controlling metastatic progression of cancer. Here, we report a label-free optical strategy using Raman spectroscopy and machine learning to identify distinct metastatic phenotypes observed in tumors formed by isogenic murine breast cancer cell lines of progressively increasing...

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Identifiers

PMID: 35910801
DOI: 10.7150/thno.74002
PMCID: PMC9330538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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