Article
Genetic Diversity and Population Genetic Analysis of Plasmodium falciparum Thrombospondin Related Anonymous Protein (TRAP) in Clinical Samples from Saudi Arabia.
Genes - 25 Jun 2022
Bin Dajem Saad M, Ahmed Md Atique, Alghnnam Fatimah F, Alghannam Shouq F, Deshmukh Gauspasha Yusuf, Zaidi Rehan Haider, Bohol Marie Fe F, Salam Syeda Sabiha, Wazid Syeda Wasfeea, Shafeai Mohammed I, Rudiny Fuad H, Motaen Ali M, Morsy Kareem, Al-Qahtani Ahmed A
Abstract excerpt
The thrombospondin related anonymous protein (TRAP) is considered one of the most important pre-erythrocytic vaccine targets. Earlier population genetic studies revealed the TRAP gene to be under strong balancing natural selection. This study is the first attempt to analyze genetic diversity, natural selection, phylogeography and population structure in 199 clinical samples from Saudi Arabia using the full-length...
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