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Article

Recombinant human chorionic gonadotropin induces signaling pathways towards cancer prevention in the breast of BRCA1/2 mutation carriers.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Mar 2023

Su Yanrong, Dang Nhi M, Depypere Herman, Santucci-Pereira Julia, Gutiérrez-Díez Pedro J, Kanefsky Joice, Janssens Jaak Ph, Russo Jose

Abstract excerpt

BACKGROUND: Strategies for breast cancer prevention in women with germline BRCA1/2 mutations are limited. We previously showed that recombinant human chorionic gonadotropin (r-hCG) induces mammary gland differentiation and inhibits mammary tumorigenesis in rats. The present study investigated hCG-induced signaling pathways in the breast of young nulliparous women carrying germline BRCA1/2 mutations. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35881946
DOI: 10.1097/CEJ.0000000000000763
PMCID: PMC9800649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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