Article

Chorionic Gonadotropin Beta 7 is a marker of immune evasion in cancer

2025-06-02

Abstract excerpt

<h4>ABSTRACT</h4> Human chorionic gonadotropin beta (beta-hCG) is an oncofetal antigen expressed by trophoblast cells of the placenta, with minimal expression in adult somatic tissues. Numerous studies have demonstrated that beta-hCG-encoding genes are expressed in various cancers, but expression of these genes ( CGB3 , CGB5 , CGB7 , and CGB8 ) across diverse cancers has not been systematically evaluated. Her...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: de28ce5c-e98b-5920-b2b4-f9058e4e193c
DOI: 10.1101/2025.05.28.656535

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Chorionic Gonadotropin Beta 7 is a marker of immune evasion in cancerDOI 10.1101/2025.05.28.656535Read

Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian CarcinomaSemantic proximity Read

sB7-H4 is a diagnostic biomarker in epithelial ovarian cancer and correlates to platinum resistanceSemantic proximity Read

PD‐L1, B7‐H3 and VISTA are highly expressed in gestational trophoblastic neoplasiaSemantic proximity Read

Role of NLRP7 in Normal and Malignant Trophoblast CellsSemantic proximity Read

Current and Evolving Biomarkers in the Diagnosis and Management of Testicular Germ Cell TumorsSemantic proximity Read

APOBEC3G Expression Correlates with T-Cell Infiltration and Improved Clinical Outcomes in High-grade Serous Ovarian CarcinomaSemantic proximity Read

Galectins: Double-edged Swords in the Cross-roads of Pregnancy Complications and Female Reproductive Tract Inflammation and NeoplasiaSemantic proximity Read

Systemic immune-inflammation index in germ-cell tumours: search for a biological prognostic biomarkerSemantic proximity Read

Fine-scale quantification of HCG beta gene transcription in human trophoblastic and non-malignant non-trophoblastic tissuesSemantic proximity Read

Progesterone limits the tumor-promoting effects of the beta-subunit of human chorionic gonadotropin via non-nuclear receptorsSemantic proximity Read

ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1.Semantic proximity Read

Melanoma Antigen Family A (MAGE A) as Promising Biomarkers and Therapeutic Targets in Bladder CancerSemantic proximity Read