Article
A susceptibility putative haplotype within NLRP3 inflammasome gene influences ischaemic stroke risk in the population of Punjab, India.
International journal of immunogenetics - 1 Aug 2022
Kumar Nitin, Kaur Manminder, Singh Gurjinderpal, Valecha Srishti, Khinda Rubanpal, Di Napoli Mario, Singh Monica, Singh Puneetpal, Mastana Sarabjit
Abstract excerpt
Despite strong genetic implications of NLRP3 inflammasome, its examination as genetic determinant of ischaemic stroke (IS) remains to be done in Punjab, which has been investigated in this study. In this case control study, 400 subjects (200 IS patients, 200 stroke free controls) were included. Contributions of 5 single nucleotide polymorphisms (SNPs) including a functional SNP within NLRP3 gene (rs10754558,...
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