Article
Tissue methylated DNA markers for sporadic pancreatic cancer are strongly associated with familial and genetically predisposed pancreatic cancer.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Sept 2022
Majumder Shounak, Taylor William R, Foote Patrick H, Gysbers Brianna J, Cao Xiaoming, Mahoney Douglas W, Burger Kelli N, Doering Karen A, Graham Rondell P, Couch Fergus J, Petersen Gloria M, Kisiel John B
Abstract excerpt
High-risk individuals (HRIs) with familial and genetic predisposition to pancreatic ductal adenocarcinoma (PDAC) are eligible for screening. There is no accurate biomarker for detecting early-stage PDAC. We previously demonstrated that a panel of methylated DNA markers (MDMs) accurately detect sporadic PDAC. In this study we compared the distribution of MDMs in DNA extracted from tissue of PDAC cases who carry...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.