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Article

Targeted Transcriptome and KRAS Mutation Analysis Improve the Diagnostic Performance of EUS-FNA Biopsies in Pancreatic Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2021

Lundy Joanne, Gao Hugh, Berry William, Masoumi-Moghoddam Samar, Jenkins Brendan J, Croagh Daniel

Abstract excerpt

PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a poor prognosis, and current diagnostic tests have suboptimal sensitivity. Incorporating standard cytology with targeted transcriptomic and mutation analysis may improve upon the accuracy of diagnostic biopsies, thus reducing the burden of repeat procedures and delays to treatment initiation. EXPERIMENTAL DESIGN: We reviewed the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34400416
DOI: 10.1158/1078-0432.CCR-21-1107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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