Defining the Comprehensive Genomic Landscapes of Pancreatic Ductal Adenocarcinoma Using Real-World Endoscopic Aspiration Samples.

doi:10.1158/1078-0432.CCR-20-2667

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Defining the Comprehensive Genomic Landscapes of Pancreatic Ductal Adenocarcinoma Using Real-World Endoscopic Aspiration Samples.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Feb 2021

Semaan Alexander, Bernard Vincent, Lee Jaewon J, Wong Justin W, Huang Jonathan, Swartzlander Daniel B, Stephens Bret M, Monberg Maria E, Weston Brian R, Bhutani Manoop S, Chang Kyle, Scheet Paul A, Maitra Anirban, Jakubek Yasminka A, Guerrero Paola A

Abstract excerpt

PURPOSE: Most patients with pancreatic ductal adenocarcinoma (PDAC) present with surgically unresectable cancer. As a result, endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is the most common biospecimen source available for diagnosis in treatment-naïve patients. Unfortunately, these limited samples are often not considered adequate for genomic analysis, precluding the opportunity for enrollment on...

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Identifiers

PMID: 33188144
DOI: 10.1158/1078-0432.CCR-20-2667
PMCID: PMC7887035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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