Article
Reliable Detection of Somatic Mutations for Pancreatic Cancer in Endoscopic Ultrasonography-Guided Fine Needle Aspirates with Next-Generation Sequencing: Implications from a Prospective Cohort Study.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Dec 2021
Habib Joseph R, Zhu Yayun, Yin Lingdi, Javed Ammar A, Ding Ding, Tenior Jonathan, Wright Michael, Ali Syed Z, Burkhart Richard A, Burns William, Wolfgang Christopher L, Shin Eunji, Yu Jun, He Jin
Abstract excerpt
BACKGROUND OR PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is commonly diagnosed by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). However, the diagnostic adequacy of EUS-FNA is often limited by low cellularity leading to inconclusive results. We aimed to investigate the feasibility and added utility of targeted next-generation sequencing (NGS) on PDAC EUS-FNAs. METHODS: EUS-FNAs were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.