Article
Targeted next generation sequencing of endoscopic ultrasound acquired cytology from ampullary and pancreatic adenocarcinoma has the potential to aid patient stratification for optimal therapy selection.
Oncotarget - 23 Aug 2016
Gleeson Ferga C, Kerr Sarah E, Kipp Benjamin R, Voss Jesse S, Minot Douglas M, Tu Zheng Jin, Henry Michael R, Graham Rondell P, Vasmatzis George, Cheville John C, Lazaridis Konstantinos N, Levy Michael J
Abstract excerpt
BACKGROUND & AIMS: Less than 10% of registered drug intervention trials for pancreatic ductal adenocarcinoma (PDAC) include a biomarker stratification strategy. The ability to identify distinct mutation subsets via endoscopic ultrasound fine needle aspiration (EUS FNA) molecular cytology could greatly aid clinical trial patient stratification and offer predictive markers. We identified chemotherapy treatment...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.