Article
Vascular Endothelial Dysfunction in Myeloproliferative Neoplasms and Gene Mutations.
International heart journal - 30 Jul 2022
Aoyama Rie, Kubota Yoshiaki, Tara Shuhei, Wakita Satoshi, Yamaguchi Hiroki, Shimizu Wataru, Takano Hitoshi
Abstract excerpt
Essential thrombocythemia (ET) and polycythemia vera (PV), are common Philadelphia-negative myeloproliferative neoplasms (MPN). Patients with MPN have a high rate of cardiovascular complications and often have acquired JAK2V617F and CALR genetic mutations. In this study, we aimed to analyze vascular endothelial function in patients with MPN.We evaluated 27 outpatients, including 10 patients diagnosed with MPN,...
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