Article
Phage Particles of Controlled Length and Genome for In Vivo Targeted Glioblastoma Imaging and Therapeutic Delivery
13 Jul 2022
Abstract excerpt
M13 bacteriophage (phage) are versatile, genetically tunable nanocarriers that have been recently adapted for use as diagnostic and therapeutic platforms. Applying p3 capsid chlorotoxin fusion with the “ inho ” circular single-stranded DNA (cssDNA) gene packaging system, we produced miniature chlorotoxin inho (CTX- inho ) phage particles with a minimum length of 50 nm that can target intracranial orthotopic...
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