Article
Mutation of M13 Bacteriophage Major Coat Protein for Increased Conjugation to Exogenous Compounds.
Bioconjugate chemistry - 20 Jun 2018
Tridgett Matthew, Lloyd James R, Kennefick Jack, Moore-Kelly Charles, Dafforn Timothy R
Abstract excerpt
Over the past ten years there has been increasing interest in the conjugation of exogenous compounds to the surface of the M13 bacteriophage. M13 offers a convenient scaffold for the development of nanoassemblies with useful functions, such as highly specific drug delivery and pathogen detection. However, the progress of these technologies has been hindered by the limited efficiency of conjugation to the...
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