Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting stem cells in myelodysplastic syndromes and acute myeloid leukemia

13 Jul 2022

Abstract excerpt

The genetic architecture of cancer has been delineated through advances in high-throughput next-generation sequencing, where the sequential acquisition of recurrent driver mutations initially targeted towards normal cells ultimately leads to malignant transformation. Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are hematologic malignancies frequently initiated by mutations in the normal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Hematopoietic Stem Cell Transplantation
Share to Histone Deacetylase Inhibitors Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35822488
DOI: 10.1111/joim.13535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting stem cells in myelodysplastic syndromes and acute myeloid leukemiaPMID 35822488Read ↗

The current and future role of stem cells in myelodysplastic syndrome therapies.Semantic proximity Read ↗

Concise Review: Preleukemic Stem Cells: Molecular Biology and Clinical Implications of the Precursors to Leukemia Stem CellsSemantic proximity Read ↗

Navigating the contested borders between myelodysplastic syndrome and acute myeloid leukemiaSemantic proximity Read ↗

Stem cell concepts in myelodysplastic syndromes: lessons and challenges.Semantic proximity Read ↗

Recent advances in acute myeloid leukemia stem cell biologySemantic proximity Read ↗

Molecular Pathogenesis and Treatment of Myelodysplastic Syndromes.Semantic proximity Read ↗

Molecular and Cellular Mechanisms of Myelodysplastic Syndrome: Implications on Targeted TherapySemantic proximity Read ↗

Allogeneic Stem Cell Transplant for Myelofibrosis and Myelodysplastic Syndromes: A Contemporary Review.Semantic proximity Read ↗

Therapeutic targeting of acute myeloid leukemia stem cellsSemantic proximity Read ↗

Recent advances in myelodysplastic syndromes: Molecular pathogenesis and its implications for targeted therapies.Semantic proximity Read ↗

The Genetic Landscape of Myelodysplastic Neoplasm Progression to Acute Myeloid Leukemia.Semantic proximity Read ↗

Evolutionary trajectories of myelodysplastic syndromes/neoplasms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.