Article
Stem cell concepts in myelodysplastic syndromes: lessons and challenges.
Journal of internal medicine - 1 May 2021
Woll P S, Jacobsen S E W
Abstract excerpt
According to the cancer stem cell (CSC) hypothesis, CSCs are the only cancer cells that can give rise to and sustain all cells that constitute a cancer as they possess inherent or acquired self-renewal potential, and their elimination is required and potentially sufficient to achieve a cure. Whilst establishing CSC identity remains challenging in most cancers, studies of low-intermediate risk myelodysplastic...
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