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Article

Molecular genetics of Parkinson's disease: Contributions and global trends.

Journal of human genetics - 1 Mar 2023

Funayama Manabu, Nishioka Kenya, Li Yuanzhe, Hattori Nobutaka

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative disorder primarily characterized by motor dysfunction. Aging is the greatest risk factor for developing PD. Recent molecular genetic studies have revealed that genetic factors, in addition to aging and environmental factors, play an important role in the development of the disorder. Studies of familial PD have identified approximately 20 different causative genes....

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Identifiers

PMID: 35821405
DOI: 10.1038/s10038-022-01058-5
PMCID: PMC9968657

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